SOPHiA GENETICS — Cyborg Score 6/10

Solid
Healthcare Technology / Precision Medicine / Data-Driven Diagnostics

Strategic Profile

SOPHiA DDM™ Platform is one of the largest technology-agnostic networks of connected healthcare institutions worldwide and is currently used by more than 750 hospital, laboratory, and biopharma institutions globally. In March 2025, the company announced it had hit the milestone of 2 million genomic profiles analysed with its Sophia DDM platform.

Cyborg Score Rationale

SOPHiA GENETICS has strong platform traction with 2M genomic profiles analyzed and 750+ institutional users, supported by marquee partnerships with Memorial Sloan Kettering, AstraZeneca, and GE Healthcare. However, profitability remains challenged with negative EPS of -$1.12 and a declining stock price ($5.34 as of Feb 2026), suggesting execution or market concerns.

Top Insights

  • 2M genomic profiles analyzed as of March 2025 demonstrates significant platform traction and network effects in data-driven diagnostics
  • 750+ institutional users across hospitals, laboratories, and biopharma firms represent broad market penetration and switching costs
  • Strategic partnerships with Memorial Sloan Kettering, AstraZeneca, GE HealthCare, Qiagen, and Hitachi validate market relevance and accelerate adoption
  • Trailing twelve-month revenue of $73.3M shows steady growth but company remains unprofitable (-$1.12 EPS), requiring operational optimization

Named Competitors

  • Flatiron Health — Oncology-focused EHR and data analytics platform
  • DNAnexus — Cloud-based genomics data management and analysis
  • Benchling — Research operations and data management platform
  • Agilent Technologies — Genomics instrumentation and software solutions

Recent Developments

  • (March 2025) SOPHiA DDM Platform reached 2 million genomic profiles analyzed milestone
  • (November 2024) Ross Muken promoted to company President from CFO/COO
  • (October 2023) Partnership announced with AstraZeneca and Memorial Sloan Kettering for expanded global adoption
  • (October 2023) Qiagen partnership for somatic variant detection collaboration

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