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Syndax Pharmaceuticals, Inc.: Business Overview, Financials & Competitive Analysis

Syndax is a commercial-stage biopharmaceutical company advancing innovative cancer therapies, with two FDA-approved products: Revuforj (revumenib), a menin inhibitor, and Niktimvo (axatilimab-csfr), a monoclonal antib...

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What's in This Report
Syndax Pharmaceuticals, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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8/ 10Strong

Cyborg Score thesis

Compelling first-to-market menin inhibitor with expanding indications and strong market traction offset by pre-profitability and...

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Industry Biopharmaceutical - Oncology
2 named competitors
3 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: September 28, 2026
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Syndax Pharmaceuticals, Inc. Overview

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Syndax is a commercial-stage biopharmaceutical company advancing innovative cancer therapies, with two FDA-approved products: Revuforj (revumenib), a menin inhibitor, and Niktimvo (axatilimab-csfr), a monoclonal antibody targeting the CSF-1 receptor. The company achieved its third FDA approval and successfully launched these two medicines in 2025, advancing toward profitability.

Strategic Profile

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Syndax generated over $275 million in 2025 sales across its two lead products, demonstrating strong commercial execution and market penetration. The company initiated REVEAL-ND, a Phase 3 trial of revumenib in newly diagnosed NPM1m AML patients, designed to support both accelerated and full FDA approval.

Competitive Landscape

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Syndax's Revuforj is a menin inhibitor for relapsed/refractory acute leukemia, while the company is expanding revumenib across multiple AML subtypes and exploring metastatic colorectal cancer. Revuforj appears to be the first approved menin inhibitor with dominant market position in its mechanism class. Niktimvo competes in the CSF-1R blocking antibody space for chronic GVHD.

Industry Context

Syndax Pharmaceuticals, Inc. operates in Biopharmaceutical - Oncology.

Key facts

Founded: 2005 · Headquarters: New York, New York · Employees: N/A · Revenue: $172.4M (FY2025) · Market cap: N/A

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The top findings that survived the multi-agent debate for Syndax Pharmaceuticals, Inc..

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Recent developments

Material events tracked by the AskCyborg corpus.

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Named competitors

Pulled from the analyst-debate framework. Click any competitor to see their Cyborg Score.

Menin Inhibitor PipelineVarious menin inhibitors in development across multiple companies→CSF-1R InhibitorsCompeting mechanisms for chronic GVHD treatment→

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Industry context

Syndax Pharmaceuticals, Inc. operates in Biopharmaceutical - Oncology. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does Syndax Pharmaceuticals, Inc. do?+
Syndax is a commercial-stage biopharmaceutical company advancing innovative cancer therapies, with two FDA-approved products: Revuforj (revumenib), a menin inhibitor, and Niktimvo (axatilimab-csfr), a monoclonal antib...
What is Syndax Pharmaceuticals, Inc.'s Cyborg Score?+
Syndax Pharmaceuticals, Inc. has a Cyborg Score of 8/10 (Strong). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Syndax Pharmaceuticals, Inc.'s main competitors?+
Named competitors include Menin Inhibitor Pipeline, CSF-1R Inhibitors. The full competitive landscape is in the AskCyborg report.
How can I get the full Syndax Pharmaceuticals, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
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The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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