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ContraFect Corp: Business Overview, Financials & Competitive Analysis

ContraFect Corp scores 2/10 on the AskCyborg Cyborg Score (Challenged). Once-promising lysin platform failed to achieve clinical-stage funding sustainability, resulting in liquidation. The company entered bankruptcy liquidation in December 2023, indicating failed clinical development, regulatory setbacks, or funding challenges that prevented commercialization. While the scientific platform was novel, execution and capitalization proved insufficient.

What is ContraFect Corp's industry? ContraFect Corp (contrafect.com) operates in Stem Cell Therapy. AskCyborg classifies ContraFect Corp under Stem Cell Therapy in its company registry.

ContraFect Corp was a clinical-stage biotechnology company focused on developing novel therapeutics for drug-resistant, life-threatening infectious diseases. The company pioneered direct lytic agents (lysins and amuri...

2/ 10Challenged

Cyborg Score thesis

Once-promising lysin platform failed to achieve clinical-stage funding sustainability, resulting in...

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Industry Stem Cell Therapy
3 named competitors
1 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: September 7, 2026
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ContraFect Corp OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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ContraFect Corp Overview

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ContraFect Corp was a clinical-stage biotechnology company focused on developing novel therapeutics for drug-resistant, life-threatening infectious diseases. The company pioneered direct lytic agents (lysins and amurin peptides) as new medical modalities to combat antibiotic-resistant pathogens. However, the company filed for Chapter 7 liquidation in December 2023.

Strategic Profile

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ContraFect's innovation centered on bacteriophage-derived lysins targeting conserved bacterial regions resistant to mutation, with lead candidate exebacase (CF-301) for prosthetic joint infections and CF-370 for gram-negative pathogens. The company held a license agreement with The Rockefeller University for gram-negative lysin research. Operations ceased following liquidation filing.

Competitive Landscape

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ContraFect competed in the antibiotic resistance therapeutics space against traditional small-molecule antibiotic developers, monoclonal antibody platforms (Regeneron, GSK), and other novel modality companies (phage therapy platforms, antimicrobial peptides). Its differentiation through bacteriophage lysins offered a novel mechanism but failed to achieve regulatory or commercial success.

Industry Context

ContraFect Corp operates in Stem Cell Therapy.

Key facts

Founded: 2008 · Headquarters: Yonkers, US · Employees: 23 · Revenue: N/A · Market cap: N/A

What the analysts stress-tested

The top findings that survived the multi-agent debate for ContraFect Corp.

  • Pioneered novel direct lytic agents (lysins) as new antibiotic class targeting antibiotic-resistant pathogens
  • Filed for Chapter 7 bankruptcy liquidation in December 2023, ending operations
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Recent developments

Material events tracked by the AskCyborg corpus.

  • December 2023Filed for Chapter 7 liquidation under U.S. Bankruptcy Court for the District of Delaware
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Named competitors

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Industry context

ContraFect Corp operates in Stem Cell Therapy. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does ContraFect Corp do?+
ContraFect Corp was a clinical-stage biotechnology company focused on developing novel therapeutics for drug-resistant, life-threatening infectious diseases. The company pioneered direct lytic agents (lysins and amuri...
What is ContraFect Corp's Cyborg Score?+
ContraFect Corp has a Cyborg Score of 2/10 (Challenged). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are ContraFect Corp's main competitors?+
Named competitors include Aicuron, Conventional Antibiotics, Monoclonal Antibodies. The full competitive landscape is in the AskCyborg report.
How can I get the full ContraFect Corp research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the ContraFect Corp research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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