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Axsome Therapeutics, Inc.: Business Overview, Financials & Competitive Analysis

Axsome Therapeutics, Inc. scores 8/10 on the AskCyborg Cyborg Score (Strong). Commercial-stage biotech with diversified CNS portfolio, strong revenue growth, and multiple near-term FDA approval catalysts creating a compelling risk-reward profile. Sales growth is rapid (up 63% and 72% the past two quarters), with analysts looking for 50%-plus gains all of next year. Multiple commercial products and late-stage pipeline catalysts.

What is Axsome Therapeutics, Inc.'s industry? Axsome Therapeutics, Inc. (axsome.com) operates in Biopharmaceutical (CNS Therapeutics). AskCyborg classifies Axsome Therapeutics, Inc. under Biopharmaceutical (CNS Therapeutics) in its company registry.

Axsome Therapeutics is a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders in the United States. Unlike many biotechs, it is not a one-dru...

8/ 10Strong

Cyborg Score thesis

Commercial-stage biotech with diversified CNS portfolio, strong revenue growth, and multiple near-term FDA approval catalysts...

Read the full analyst-debate transcript →
Industry Biopharmaceutical (CNS Therapeutics)
4 named competitors
4 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: September 14, 2026
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Axsome Therapeutics, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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Axsome Therapeutics, Inc. Overview

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Axsome Therapeutics is a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders in the United States. Unlike many biotechs, it is not a one-drug outfit with three products on the market now and more to come. The company demonstrated strong momentum with full year 2025 net product revenue of $638.5 million, representing 66% annual growth.

Strategic Profile

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Axsome's stable $800M+ revenue base caps downside and supports ongoing operations, shifting risk from existential to executional and enabling pipeline-driven upside. Auvelity (for major depressive disorder) is the big draw with sales up 69% in Q3, with management thinking peak sales could be $2 billion or so, about four times current run-rate basis. Two drugs are likely to get FDA approval in 2026: AXS-12 targeting narcolepsy ($500 million opportunity) and AXS-05 for Alzheimer's agitation with potential into the $1.5 billion range or more (approval likely in first half of 2026).

Competitive Landscape

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Axsome competes in the CNS disorder treatment market with products addressing depression, Alzheimer's disease, narcolepsy, fibromyalgia, and sleep disorders. Key competitors include larger pharmaceutical companies developing similar CNS therapies, though Axsome's differentiated mechanism-of-action portfolio and commercial execution distinguish its positioning in the growing neuroscience market.

Industry Context

Axsome Therapeutics, Inc. operates in Biopharmaceutical (CNS Therapeutics).

Key facts

Founded: 2012 · Headquarters: New York, US · Employees: 683 · Revenue: $638.5M (2025) · Market cap: $37B

What the analysts stress-tested

The top findings that survived the multi-agent debate for Axsome Therapeutics, Inc..

  • Sunosi is showing solid growth for sleep apnea (sales up 35% last quarter) with recent launch of Symbravo for acute migraines.
  • Axsome has another drug in Phase III trials (for ADHD and other indications) that it thinks can be another $1 billion producer.
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Recent developments

Material events tracked by the AskCyborg corpus.

  • January 2026Axsome initiates FORWARD Phase 3 trial of AXS-14 for fibromyalgia management
  • January 2026FDA accepts priority review of AXS-05 sNDA for Alzheimer's disease agitation
  • +2 moreTrack every material event for Axsome Therapeutics, Inc. as it happens. Explore monitoring →
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Named competitors

Pulled from the analyst-debate framework. Click any competitor to see their Cyborg Score.

CymbaltaDepression and anxiety treatment→LexaproSelective serotonin reuptake inhibitor for depression→ModafinilWakefulness-promoting agent for narcolepsy→LyricaFibromyalgia and neuropathic pain treatment→

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Industry context

Axsome Therapeutics, Inc. operates in Biopharmaceutical (CNS Therapeutics). See how the rest of the sector scores on the Cyborg framework.

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Every report is stress-tested by a panel of AI analysts arguing across 11 dimensions. The output is the part of the case that survived pushback.

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Frequently asked questions

What does Axsome Therapeutics, Inc. do?+
Axsome Therapeutics is a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders in the United States. Unlike many biotechs, it is not a one-dru...
What is Axsome Therapeutics, Inc.'s Cyborg Score?+
Axsome Therapeutics, Inc. has a Cyborg Score of 8/10 (Strong). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Axsome Therapeutics, Inc.'s main competitors?+
Named competitors include Cymbalta, Lexapro, Modafinil, Lyrica. The full competitive landscape is in the AskCyborg report.
How can I get the full Axsome Therapeutics, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the Axsome Therapeutics, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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