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Syros Pharmaceuticals, Inc.: Business Overview, Financials & Competitive Analysis

Syros Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to developing innovative medicines that control gene expression. With a focus on the discovery and development of novel gene...

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Company OverviewProduct PortfolioLeadership and Management TeamFinancial Overview of Syros Pharmaceuticals, Inc.Marketing StrategiesSyros Pharmaceuticals, Inc. Market Research and Competitors
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3/10Challenged
Syros Pharmaceuticals, Inc.

Biotech company at critical inflection point following failed flagship trial and planned Nasdaq delisting, facing significant execution risk despite innovative gene control...

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3/ 10Challenged

Cyborg Score thesis

Biotech company at critical inflection point following failed flagship trial and planned Nasdaq delisting, facing significant...

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Industry Biopharmaceutical - Hematologic Malignancies & Gene Control Therapeutics
3 named competitors
4 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: August 24, 2026
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Syros Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to developing innovative medicines that control gene expression. With a focus on the discovery and development of novel gene control therapies, Syros is at the forefront of a new wave of treatments aimed at addressing diseases with high unmet medical needs.

Company Overview

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Syros Pharmaceuticals, Inc. was founded in 2012 and is headquartered in Cambridge, Massachusetts. The company utilizes its proprietary gene control platform to identify and drug novel targets linked to genomically defined diseases. Syros’ mission is to transform patients’ lives through the creation of treatments that are not only effective but also specific to the underlying mechanisms of their diseases.

Product Portfolio

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Syros Pharmaceuticals’ product portfolio is predominantly focused on oncology and monogenic diseases. Their lead product candidates include:

  • SY-1425: A selective retinoic acid receptor alpha (RARα) agonist for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
  • SY-5609: A highly selective and potent oral CDK7 inhibitor for solid tumors, including breast, colorectal, and lung cancers.
  • SY-2101: An oral form of arsenic trioxide for patients with acute promyelocytic leukemia (APL).

Leadership and Management Team

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Syros Pharmaceuticals is led by a team of seasoned professionals who bring extensive experience in drug discovery, development, and commercialization:

  • Nancy Simonian, M.D.: Chief Executive Officer
  • David A. Roth, M.D.: Chief Medical Officer
  • Kristin Stephens: Chief Development Officer

Financial Overview of Syros Pharmaceuticals, Inc.

Syros Pharmaceuticals, Inc. has shown a strong financial stance with a focus on strategic investments in their research and development programs. Key financial metrics include:

  • Revenue: $15 million (2022)
  • Research and Development Expenses: $75 million (2022)
  • Cash and Cash Equivalents: $100 million (2022)

Marketing Strategies

Syros Pharmaceuticals employs a targeted marketing strategy focused on building awareness among healthcare professionals, investors, and patients. They leverage scientific publications, conferences, and digital marketing to communicate their progress and innovations.

Syros Pharmaceuticals, Inc. Market Research and Competitors

Syros operates in a highly competitive biopharmaceutical market. Key competitors include companies like Gilead Sciences, Bristol-Myers Squibb, and Novartis. Despite the competition, Syros differentiates itself through its unique gene control platform and targeted approach to drug development.

Sales Strategies

Syros Pharmaceuticals has yet to commercialize its products as they are still in clinical development. Their sales strategies will likely involve partnerships with larger pharmaceutical companies and direct sales to healthcare institutions upon regulatory approval.

Technologies Utilized

Key technologies and innovations at Syros Pharmaceuticals include:

  • Gene Control Platform: Proprietary technology for identifying and drugging novel genomic targets.
  • CDK7 Inhibition: Targeting cyclin-dependent kinase 7 to halt cancer cell proliferation.

HR Practices

Syros Pharmaceuticals is committed to fostering a collaborative and inclusive work environment. They emphasize professional development, diversity, and employee well-being as core components of their HR practices.

Corporate Responsibility

Syros Pharmaceuticals is dedicated to corporate social responsibility, focusing on ethical research practices, community engagement, and environmental sustainability. They actively participate in initiatives that support patient communities and scientific education.

Future Plans

Looking ahead, Syros Pharmaceuticals plans to advance its clinical programs, expand its gene control platform, and explore strategic partnerships to bring its innovative therapies to market. They are committed to addressing unmet medical needs and improving patient outcomes globally.


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Recent developments

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Named competitors

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Oncology ProgramsEstablished cancer therapeutic portfolioHematologic Malignancy TreatmentsMarket leader in multiple myeloma and related conditionsGene-Targeted TherapeuticsGene control and editing platform company

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Industry context

Syros Pharmaceuticals, Inc. operates in Biopharmaceutical - Hematologic Malignancies & Gene Control Therapeutics. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does Syros Pharmaceuticals, Inc. do?+
Syros Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to developing innovative medicines that control gene expression. With a focus on the discovery and development of novel gene...
What is Syros Pharmaceuticals, Inc.'s Cyborg Score?+
Syros Pharmaceuticals, Inc. has a Cyborg Score of 3/10 (Challenged). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Syros Pharmaceuticals, Inc.'s main competitors?+
Named competitors include Oncology Programs, Hematologic Malignancy Treatments, Gene-Targeted Therapeutics. The full competitive landscape is in the AskCyborg report.
How can I get the full Syros Pharmaceuticals, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
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The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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