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ALNYLAM PHARMACEUTICALS, INC.: Business Overview, Financials & Competitive Analysis

ALNYLAM PHARMACEUTICALS, INC. is a pioneering biopharmaceutical company dedicated to the development of RNA interference (RNAi) therapeutics. Founded in 2002 and headquartered in Cambridge,...

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Company OverviewProduct PortfolioLeadership and Management TeamFinancial OverviewMarketing StrategiesMarket Overview and Competitors
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8/10Strong
Alnylam Pharmaceuticals, Inc.

Alnylam transitions from speculative biotech to profitable pharma leader with dominant RNAi platform and high-growth blockbuster in competitive ATTR market.

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Competitors covered:Pfizer Inc.
8/ 10Strong

Cyborg Score thesis

Alnylam transitions from speculative biotech to profitable pharma leader with dominant RNAi platform and high-growth blockbuster...

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Industry Biopharmaceuticals - RNA Interference (RNAi) Therapeutics
3 named competitors
3 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: August 17, 2026
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ALNYLAM PHARMACEUTICALS, INC. is a pioneering biopharmaceutical company dedicated to the development of RNA interference (RNAi) therapeutics. Founded in 2002 and headquartered in Cambridge, Massachusetts, ALNYLAM PHARMACEUTICALS, INC. has established itself as a leader in the field of genetic medicine, focusing on innovative treatments for rare genetic, cardio-metabolic, and hepatic infectious diseases.

Company Overview

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ALNYLAM PHARMACEUTICALS, INC. has revolutionized the pharmaceutical landscape with its commitment to RNAi technology. This approach allows for the silencing of specific genes responsible for disease, offering a new avenue for treating conditions that were previously considered untreatable. The company’s mission is to harness the power of RNAi to transform the lives of patients around the world.

Product Portfolio

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ALNYLAM PHARMACEUTICALS, INC. offers a diverse range of products, including:

  • ONPATTRO® (patisiran) – For the treatment of hereditary transthyretin-mediated amyloidosis.
  • GIVLAARI® (givosiran) – For the treatment of acute hepatic porphyria.
  • OXBRYTA® (voxelotor) – For the treatment of sickle cell disease.
  • AMVUTTRA® (vutrisiran) – For the treatment of ATTR amyloidosis.

Leadership and Management Team

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The success of ALNYLAM PHARMACEUTICALS, INC. can be attributed to its visionary leadership team, including:

  • John Maraganore, Ph.D. – CEO
  • Barry Greene – President
  • Akshay Vaishnaw, M.D., Ph.D. – President of R&D
  • Manmeet S. Soni – CFO

Financial Overview

ALNYLAM PHARMACEUTICALS, INC. has demonstrated robust financial performance, with key metrics including:

  • Revenue: $886 million (2022)
  • R&D Expenditure: $737 million (2022)
  • Market Cap: $16 billion

Marketing Strategies

ALNYLAM PHARMACEUTICALS, INC. employs a multi-faceted marketing strategy that includes:

  • Targeted outreach to healthcare professionals
  • Comprehensive patient education programs
  • Digital marketing campaigns
  • Collaborations with patient advocacy groups

Market Overview and Competitors

The biopharmaceutical market is highly competitive, with key players including:

  • Ionis Pharmaceuticals
  • Sarepta Therapeutics
  • Moderna, Inc.
  • Regeneron Pharmaceuticals

Sales Strategies

ALNYLAM PHARMACEUTICALS, INC. utilizes a direct sales model supplemented by strategic partnerships, focusing on:

  • Building strong relationships with key opinion leaders
  • Expanding global footprint through partnerships
  • Leveraging digital tools for sales enablement

Technologies Utilized

ALNYLAM PHARMACEUTICALS, INC. leverages cutting-edge technologies, such as:

  • RNAi technology
  • Lipid nanoparticle delivery systems
  • Advanced genomics and bioinformatics

HR Practices

ALNYLAM PHARMACEUTICALS, INC. is committed to fostering a positive work environment, with practices including:

  • Comprehensive employee benefits
  • Continuous learning and development programs
  • Diversity and inclusion initiatives

Corporate Responsibility

ALNYLAM PHARMACEUTICALS, INC. is dedicated to corporate social responsibility, focusing on:

  • Environmental sustainability
  • Community engagement initiatives
  • Ethical business practices

Future Plans

ALNYLAM PHARMACEUTICALS, INC. aims to expand its therapeutic pipeline, explore new indications for existing products, and continue to innovate in the field of RNAi therapeutics. The company is committed to maintaining its leadership position in the biopharmaceutical industry through strategic investments in research and development.

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Recent developments

Material events tracked by the AskCyborg corpus.

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Named competitors

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VyndaqelOral TTR stabilizer, current market leader in ATTR with 2028 patent expirationAttrubyTTR stabilizer approved late 2024, closest competitor for first-line ATTR therapyWainuaRNAi silencer with major advantage from AstraZeneca's cardiovascular sales force

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Industry context

ALNYLAM PHARMACEUTICALS, INC. operates in Biopharmaceuticals - RNA Interference (RNAi) Therapeutics. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does ALNYLAM PHARMACEUTICALS, INC. do?+
ALNYLAM PHARMACEUTICALS, INC. is a pioneering biopharmaceutical company dedicated to the development of RNA interference (RNAi) therapeutics. Founded in 2002 and headquartered in Cambridge,...
What is ALNYLAM PHARMACEUTICALS, INC.'s Cyborg Score?+
ALNYLAM PHARMACEUTICALS, INC. has a Cyborg Score of 8/10 (Strong). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are ALNYLAM PHARMACEUTICALS, INC.'s main competitors?+
Named competitors include Vyndaqel, Attruby, Wainua. The full competitive landscape is in the AskCyborg report.
How can I get the full ALNYLAM PHARMACEUTICALS, INC. research report?+
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How current is the ALNYLAM PHARMACEUTICALS, INC. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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