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HilleVax, Inc.: Business Overview, Financials & Competitive Analysis

HilleVax is a clinical-stage biopharmaceutical company developing and commercializing vaccines. The company develops HIL-214, a virus-like particle-based vaccine candidate for the prevention of moderate-to-severe acut...

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HilleVax, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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4/ 10Mixed

Cyborg Score thesis

Clinical-stage vaccine biotech with differentiated VLP platform for norovirus, trading at distressed valuations with near-term...

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Industry Biopharmaceutical/Vaccines
4 named competitors
3 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: June 15, 2026
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HilleVax, Inc. Overview

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HilleVax is a clinical-stage biopharmaceutical company developing and commercializing vaccines. The company develops HIL-214, a virus-like particle-based vaccine candidate for the prevention of moderate-to-severe acute gastroenteritis caused by norovirus infection. It has a license agreement with Takeda Vaccines, Inc. to develop and commercialize HIL-214 pharmaceutical products.

Strategic Profile

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HilleVax's primary focus is its VLP-based vaccine candidate HIL-214, where VLP technology mimics the structure and antigenic properties of viruses without containing infectious genetic material, thereby triggering effective immunogenic responses in the host. As of March 2025, HilleVax had cash of $160m and no debt, with annual cash burn of $90m, providing approximately 21 months of cash runway.

Competitive Landscape

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Competitors include Moderna, Vaxart, Merck & Co., BioNTech, and CSL Behring. HilleVax differentiates through its specialized VLP platform targeting norovirus, an underserved indication with significant pediatric and geriatric populations. The company faces competition from larger, better-capitalized vaccine manufacturers.

Industry Context

HilleVax, Inc. operates in Biopharmaceutical/Vaccines.

Key facts

Founded: 2019 · Headquarters: Boston, US · Employees: 14 · Market cap: $95M

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Recent developments

Material events tracked by the AskCyborg corpus.

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Named competitors

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mRNA VaccinesmRNA-based vaccine platform with multiple approved productsOral Vaccine PlatformOral vaccine development for infectious diseasesDiversified VaccinesLarge pharmaceutical company with extensive vaccine portfoliomRNA/VLP PlatformmRNA-based therapeutic and vaccine development

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Industry context

HilleVax, Inc. operates in Biopharmaceutical/Vaccines. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does HilleVax, Inc. do?+
HilleVax is a clinical-stage biopharmaceutical company developing and commercializing vaccines. The company develops HIL-214, a virus-like particle-based vaccine candidate for the prevention of moderate-to-severe acut...
What is HilleVax, Inc.'s Cyborg Score?+
HilleVax, Inc. has a Cyborg Score of 4/10 (Mixed). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are HilleVax, Inc.'s main competitors?+
Named competitors include mRNA Vaccines, Oral Vaccine Platform, Diversified Vaccines, mRNA/VLP Platform. The full competitive landscape is in the AskCyborg report.
How can I get the full HilleVax, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the HilleVax, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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