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Cogent Biosciences, Inc.: Business Overview, Financials & Competitive Analysis

Cogent Biosciences is a biotechnology company developing real solutions to treat genetically driven diseases, leveraging validated biology to address the true underlying drivers of disease and provide real hope for pa...

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Cogent Biosciences, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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8/ 10Strong

Cyborg Score thesis

Precision oncology player with compelling Phase 3 data and multiple 2026 NDA filings targeting rare, underserved diseases offers...

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Industry Biotechnology
3 named competitors
3 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: November 2, 2026
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Cogent Biosciences, Inc. Overview

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Cogent Biosciences is a biotechnology company developing real solutions to treat genetically driven diseases, leveraging validated biology to address the true underlying drivers of disease and provide real hope for patients. The company's lead program, bezuclastinib, is designed to selectively and potently inhibit exon 17 mutations found within the KIT receptor tyrosine kinase, including KIT D816V which drives Systemic Mastocytosis, and is also found in gastrointestinal stromal tumors (GIST).

Strategic Profile

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Bezuclastinib has exhibited promising initial data across all three trials (APEX in AdvSM, SUMMIT in NonAdvSM and PEAK in GIST), including an encouraging safety profile across 600+ patients in single agent and combination dosing. The company submitted a New Drug Application (NDA) for NonAdvSM in December 2025, with NDA submissions for AdvSM on track for 1H 2026 and GIST on track for April 2026.

Competitive Landscape

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Blueprint Medicines, Kite Pharma, Senti Bio, NexImmune, and Apollomics are among the 77 competitors of Cogent Biosciences. Cogent's focused approach to KIT-driven diseases and its combination therapy strategy differentiate it within the oncology and rare disease precision medicine space, where companies like Blueprint Medicines also target genetically defined cancers.

Industry Context

Cogent Biosciences, Inc. operates in Biotechnology.

Key facts

Founded: 2014 · Headquarters: Waltham, Massachusetts · Employees: 205 · Market cap: $5.66B

What the AI analysts debated

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Recent developments

Material events tracked by the AskCyborg corpus.

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Named competitors

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Blueprint MedicinesPrecision medicine for genetically defined cancers→Kite PharmaCell therapy and oncology innovations→Ventyx BiosciencesImmunology and precision therapeutics→

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Industry context

Cogent Biosciences, Inc. operates in Biotechnology. See how the rest of the sector scores on the Cyborg framework.

Top companies in Biotechnology by Cyborg Score

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Frequently asked questions

What does Cogent Biosciences, Inc. do?+
Cogent Biosciences is a biotechnology company developing real solutions to treat genetically driven diseases, leveraging validated biology to address the true underlying drivers of disease and provide real hope for pa...
What is Cogent Biosciences, Inc.'s Cyborg Score?+
Cogent Biosciences, Inc. has a Cyborg Score of 8/10 (Strong). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Cogent Biosciences, Inc.'s main competitors?+
Named competitors include Blueprint Medicines, Kite Pharma, Ventyx Biosciences. The full competitive landscape is in the AskCyborg report.
How can I get the full Cogent Biosciences, Inc. research report?+
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The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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