Arcutis Biotherapeutics, Inc. Overview
Pro stress-test →Arcutis Biotherapeutics is a commercial-stage medical dermatology company that champions meaningful innovation to address the urgent needs of individuals living with immune-mediated dermatological diseases and conditions. Its lead product is ZORYVE, a topical roflumilast cream for the treatment of plaque psoriasis and atopic dermatitis.
Strategic Profile
Pro stress-test →Arcutis employs a precision-medicine approach to deliver topical therapies designed to improve efficacy and tolerability compared with existing treatment options. The company reported Q4 2025 net profit of US$17.4 million and raised 2026 net product revenue guidance to US$480 million–US$495 million, with rapid ZORYVE uptake across expanded indications translating into improving profitability.
Competitive Landscape
Pro stress-test →Arcutis competes in the immuno-inflammatory skin disease market with clinical development efforts centered on targeted treatments for plaque psoriasis, atopic dermatitis, seborrheic dermatitis and vitiligo using a precision-medicine approach with topical therapies. Key competitors include JAK inhibitor manufacturers and other topical dermatology companies in the inflammatory skin disease space.
Industry Context
Arcutis Biotherapeutics, Inc. operates in Biopharmaceuticals / Medical Dermatology.
Key facts
Founded: 2016 · Headquarters: Westlake Village, United States · Revenue: $376.07M (2025 full-year) · Market cap: $3.50B