✨ Free AI Report
Applied Therapeutics, Inc.: Key Facts, Business Model & Financial Analysis Read the overview below or get the full interactive report with Cyborg Score, analyst debate audio & saved-company playlists — free, no credit card.
Get Free Report →
Home Research Preview Applied Therapeutics, Inc.
Research Preview

Applied Therapeutics, Inc.: Business Overview, Financials & Competitive Analysis

Applied Therapeutics was acquired by Cycle Group Holdings on February 3, 2026, concluding its journey as a clinical-stage biopharmaceutical company. The company developed govorestat (AT-007), a CNS-penetrant Aldose Re...

Analyst-debate audio for Applied Therapeutics, Inc.

AskCyborg analysts argue the bull and bear cases for Applied Therapeutics, Inc. across 11 stress-tested dimensions. Listen on your commute -- faster than reading the 30-page report.

Play the free intro →
Free intro · Pro unlocks the full analyst debate
What's in This Report
Applied Therapeutics, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
Get Interactive Report Freeor start reading below
3/ 10Challenged

Cyborg Score thesis

Distressed biotech acquisition reflecting clinical setbacks and cash burn that forced near-term strategic...

Read the full analyst-debate transcript →
Industry Clinical-stage Biopharmaceuticals / Rare Metabolic Diseases
1 named competitors
4 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: September 14, 2026
AI-Verified Research
30+ Page Report

Get the Latest Applied Therapeutics, Inc. Report

Up-to-date AI-powered research, analyst debate audio & saved-company playlists

Get Current Report Free
✓ No credit card required
or get it by email

Applied Therapeutics, Inc. Overview

Pro stress-test →

Applied Therapeutics was acquired by Cycle Group Holdings on February 3, 2026, concluding its journey as a clinical-stage biopharmaceutical company. The company developed govorestat (AT-007), a CNS-penetrant Aldose Reductase Inhibitor for rare metabolic diseases including Classic Galactosemia, CMT-SORD Deficiency, and PMM2-CDG.

Strategic Profile

Pro stress-test →

Before acquisition, Applied Therapeutics reduced workforce by approximately 46% and implemented cost-containment measures, reflecting challenges in its development pipeline. The company completed FDA Type C meetings for govorestat in CMT-SORD and received FDA written feedback on galactosemia data, evaluating next steps.

Competitive Landscape

Pro stress-test →

Govorestat competes in the rare metabolic disease treatment space, targeting CNS-penetrant aldose reductase inhibition for galactosemia and sorbitol dehydrogenase deficiency. The acquisition by Cycle Group reflects consolidation in the biotech sector where smaller clinical-stage companies face significant capital and regulatory hurdles.

Industry Context

Applied Therapeutics, Inc. operates in Clinical-stage Biopharmaceuticals / Rare Metabolic Diseases.

Key facts

Founded: 2016 · Headquarters: New York, United States

What the analysts stress-tested

The top findings that survived the multi-agent debate for Applied Therapeutics, Inc..

+2 more stress-tested counter-arguments unlock with Pro. Read the full analyst debate →

Recent developments

Material events tracked by the AskCyborg corpus.

Get alerted when Applied Therapeutics, Inc. has a new material development →

Named competitors

Pulled from the analyst-debate framework. Click any competitor to see their Cyborg Score.

Rare metabolic disease treatmentsParent company integrating govorestat into broader rare disease portfolio→

Compare Applied Therapeutics, Inc. with another company

Pick any company in the AskCyborg corpus to see side-by-side Cyborg Scores and insights.

vs
Side-by-side opens in your AskCyborg account

Industry context

Applied Therapeutics, Inc. operates in Clinical-stage Biopharmaceuticals / Rare Metabolic Diseases. See how the rest of the sector scores on the Cyborg framework.

Browse Clinical-stage Biopharmaceuticals / Rare Metabolic Diseases research →
NEW · MCP server

Ask your AI assistant about Applied Therapeutics, Inc.

Install the free AskCyborg MCP server in Claude, Cursor, Cline, Continue, or Windsurf and ask any of these in-line:

“Compare Applied Therapeutics, Inc. and its top competitor on Cyborg Score”
“What did Applied Therapeutics, Inc. do this quarter?”
“Is Applied Therapeutics, Inc. a defensible business in 5 years?”
Install the MCP server (10 sec) →
Free, anonymous, no API key required

How AskCyborg builds confidence

⚔

Analyst debate, not single-author opinion

Every report is stress-tested by a panel of AI analysts arguing across 11 dimensions. The output is the part of the case that survived pushback.

📊

Recalibrated weekly

The Cyborg Score is recomputed weekly against fresh data. Recent material developments are continuously tracked and surfaced.

🔗

Methodology open at /methodology

The framework, dimensions, and band breakdowns are documented. The same company gets the same score from any analyst running the framework.

🔒

Free tier is free

No credit card to read the research. Pro adds saved-company audio playlists, monitoring, audio briefings on demand, and PDF export for $39/mo annual.

Sources: public filings, regulatory data, news flow, and proprietary analyst signals. Read the methodology →

Frequently asked questions

What does Applied Therapeutics, Inc. do?+
Applied Therapeutics was acquired by Cycle Group Holdings on February 3, 2026, concluding its journey as a clinical-stage biopharmaceutical company. The company developed govorestat (AT-007), a CNS-penetrant Aldose Re...
What is Applied Therapeutics, Inc.'s Cyborg Score?+
Applied Therapeutics, Inc. has a Cyborg Score of 3/10 (Challenged). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Applied Therapeutics, Inc.'s main competitors?+
Named competitors include Rare metabolic disease treatments. The full competitive landscape is in the AskCyborg report.
How can I get the full Applied Therapeutics, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the Applied Therapeutics, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

Track Applied Therapeutics, Inc. over time

Pro members get saved-company audio playlists, Cyborg Score recalibrations, and monitoring for material events across the AskCyborg corpus.

See Pro features
From $39/mo annual

More Clinical-stage Biopharmaceuticals research

Companies in the same sector and named competitors, ranked by Cyborg Score.

7AtaiBeckley Inc.7NervGen Pharma Corp7Trevi Therapeutics, Inc.6Disc Medicine, Inc.6Sagimet Biosciences Inc.4OnKure Therapeutics, Inc.4Pliant Therapeutics, Inc.