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Shattuck Labs, Inc.: Business Overview, Financials & Competitive Analysis

Shattuck Labs, Inc. scores 6/10 on the AskCyborg Cyborg Score (Solid). DR3 pathway validation at the clinic with multi-year runway offers steady-state risk/reward in a validated immunology market. The company achieved IND clearance for SL-325 in August 2025 with first participants dosed in Phase 1 in Q3 2025, with enrollment expected complete by Q2 2026 and initial data expected by.

What is Shattuck Labs, Inc.'s industry? Shattuck Labs, Inc. (shattucklabs.com) operates in Biopharmaceuticals / Clinical-Stage Immunology. AskCyborg classifies Shattuck Labs, Inc. under Biopharmaceuticals / Clinical-Stage Immunology in its company registry.

Shattuck Labs is a biotechnology company developing antibodies for the treatment of inflammatory and immune-mediated diseases. The company is pioneering the development of potentially first-in-class monoclonal and bis...

6/ 10Solid

Cyborg Score thesis

DR3 pathway validation at the clinic with multi-year runway offers steady-state risk/reward in a validated immunology...

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Industry Biopharmaceuticals / Clinical-Stage Immunology
4 named competitors
4 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: October 19, 2026
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Shattuck Labs, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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Shattuck Labs, Inc. Overview

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Shattuck Labs is a biotechnology company developing antibodies for the treatment of inflammatory and immune-mediated diseases. The company is pioneering the development of potentially first-in-class monoclonal and bispecific DR3-blocking antibodies. As a clinical-stage biotech with $86M in cash (Q3 2025), Shattuck is advancing its lead candidate SL-325 through Phase 1 trials targeting inflammatory bowel disease (IBD).

Strategic Profile

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The company's lead asset SL-325 is being advanced through multiple Phase 2 clinical trials focusing on Inflammatory Bowel Disease (IBD). Shattuck closed a private placement of up to $103 million in August 2025 expected to fund operations into 2029. The company is strategically positioned in the high-potential TNF superfamily receptor pathway with experienced leadership additions from J&J/Janssen and OrbiMed.

Competitive Landscape

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Shattuck competes in the immunology/IBD therapeutics space against major pharma (Janssen, Gilead, AbbVie) and emerging biotech (Foghorn Therapeutics, C4 Therapeutics). Its differentiation rests on the first-in-class DR3 mechanism and bispecific platform enabling combination potential. Market size and clinical validation of TNF pathways provide tailwinds.

Industry Context

Shattuck Labs, Inc. operates in Biopharmaceuticals / Clinical-Stage Immunology.

Key facts

Founded: 2016 · Headquarters: Austin, US · Employees: 44 · Market cap: $286.66M

What the AI analysts debated

AI-generated and not independently verified: selected findings from the multi-agent debate on Shattuck Labs, Inc..

  • IND effective for SL-325 (August 2025) with Phase 1 enrollment on track for Q2 2026 data readout
  • Well-capitalized through 2029 with $86.1M cash post-private placement; net loss narrowing ($10.1M in Q3 2025)
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Recent developments

Material events tracked by the AskCyborg corpus.

  • February 2026Announced participation in TD Cowen and Leerink March 2026 healthcare conferences
  • December 2025Granted inducement equity awards to newly hired non-executive officer
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Named competitors

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Industry context

Shattuck Labs, Inc. operates in Biopharmaceuticals / Clinical-Stage Immunology. See how the rest of the sector scores on the Cyborg framework.

Top companies in Biopharmaceuticals by Cyborg Score

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Frequently asked questions

What does Shattuck Labs, Inc. do?+
Shattuck Labs is a biotechnology company developing antibodies for the treatment of inflammatory and immune-mediated diseases. The company is pioneering the development of potentially first-in-class monoclonal and bis...
What is Shattuck Labs, Inc.'s Cyborg Score?+
Shattuck Labs, Inc. has a Cyborg Score of 6/10 (Solid). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Shattuck Labs, Inc.'s main competitors?+
Named competitors include Foghorn Therapeutics (FHTX), C4 Therapeutics (CCCC), Janssen/J&J IBD Portfolio, Gilead/Galapagos Filgotinib. The full competitive landscape is in the AskCyborg report.
How can I get the full Shattuck Labs, Inc. research report?+
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How current is the Shattuck Labs, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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