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Jaguar Health, Inc.: Business Overview, Financials & Competitive Analysis

Jaguar Health, Inc. scores 4/10 on the AskCyborg Cyborg Score (Mixed). Plant-based therapeutics company with promising crofelemer program across multiple indications, but severely capital-constrained with significant near-term execution and dilution risks. Jaguar faces headwinds as a commercial-stage biotech with a market cap of only ~$3.7M and declining stock price momentum (currently $0.85 vs. 52-week high of $15.75). However, the company.

What is Jaguar Health, Inc.'s industry? Jaguar Health, Inc. (jaguar.health) operates in Biotechnology/Pharmaceuticals - Gastrointestinal Therapeutics. AskCyborg classifies Jaguar Health, Inc. under Biotechnology/Pharmaceuticals - Gastrointestinal Therapeutics in its company registry.

Jaguar Health is a commercial stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointest...

4/ 10Mixed

Cyborg Score thesis

Plant-based therapeutics company with promising crofelemer program across multiple indications, but severely capital-constrained...

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Industry Biotechnology/Pharmaceuticals - Gastrointestinal Therapeutics
2 named competitors
4 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: October 19, 2026
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Jaguar Health, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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Jaguar Health, Inc. Overview

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Jaguar Health is a commercial stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointestinal distress, specifically associated with overactive bowel. The company operates through two segments—Human Health and Animal Health—with approved products and multiple clinical programs advancing through development.

Strategic Profile

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The lead product Mytesi (crofelemer) is an oral plant-based prescription drug made from sustainable sources and is FDA-approved for treatment of noninfectious diarrhea in adults with HIV/AIDS on antiretroviral therapy and generates revenue. The company is expanding crofelemer across multiple indications including cancer-related diarrhea, rare diseases, and animal health applications while maintaining a focus on plant-based, non-opioid therapeutic solutions.

Competitive Landscape

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Jaguar competes in the GI therapeutics and rare disease space with other biotech companies pursuing anti-diarrheal and GI disorder treatments. Key differentiator is the plant-based, sustainable sourcing strategy and dual Human/Animal Health segments. Competitors include other antidiarrheal developers and broader GI therapeutics companies, though Jaguar's botanical approach and crofelemer's unique mechanism provide some competitive insulation.

Industry Context

Jaguar Health, Inc. operates in Biotechnology/Pharmaceuticals - Gastrointestinal Therapeutics.

Key facts

Founded: 2013 · Headquarters: San Francisco, California · Employees: 49 · Market cap: $3.7M

What the AI analysts debated

AI-generated and not independently verified: selected findings from the multi-agent debate on Jaguar Health, Inc..

  • FDA-approved Mytesi generates revenue for HIV/AIDS-related diarrhea; company pursuing label expansion across cancer, rare diseases, and IBS indications
  • Recently submitted amended protocol to FDA for potential expedited approval pathway for crofelemer in microvillus inclusion disease (MVID)
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Recent developments

Material events tracked by the AskCyborg corpus.

  • January 2026Jaguar Animal Health granted U.S. rights to crofelemer drugs and entered license agreement with Future Pak
  • December 2025FDA awarded $240,000 grant in support of Canalevia-CA1; company presented promising crofelemer trial results
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Named competitors

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Industry context

Jaguar Health, Inc. operates in Biotechnology/Pharmaceuticals - Gastrointestinal Therapeutics. See how the rest of the sector scores on the Cyborg framework.

Top companies in Biotechnology by Cyborg Score

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Frequently asked questions

What does Jaguar Health, Inc. do?+
Jaguar Health is a commercial stage pharmaceuticals company focused on developing novel proprietary prescription medicines sustainably derived from plants from rainforest areas for people and animals with gastrointest...
What is Jaguar Health, Inc.'s Cyborg Score?+
Jaguar Health, Inc. has a Cyborg Score of 4/10 (Mixed). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Jaguar Health, Inc.'s main competitors?+
Named competitors include Anti-secretory antidiarrheal agents, GI disorder therapeutics. The full competitive landscape is in the AskCyborg report.
How can I get the full Jaguar Health, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the Jaguar Health, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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