DiaMedica Therapeutics Inc. — Cyborg Score 5/10

Mixed
Clinical-stage biopharmaceutical development

Strategic Profile

The ReMEDy2 Phase 2/3 AIS Trial of DM199 surpassed 70% of required interim enrollment, with interim analysis planned in Q4 2026. Management anticipates four separate preeclampsia data readouts and a readout from the fetal growth restriction trial between now and the end of 2027, with these datasets anticipated to inform dose selection for a potential multi-national Phase 3 program in early-onset preeclampsia.

Cyborg Score Rationale

The company has incurred cumulative losses of $182.8 million since inception in 2000. However, DiaMedica maintains $51.3 million in cash, cash equivalents and investments with anticipated runway through 2027, supporting advancement of multiple late-stage clinical programs approaching key inflection points.

Top Insights

  • (May 2026) ReMEDy2 Phase 2/3 acute ischemic stroke trial >70% enrolled; interim analysis expected Q4 2026
  • (March 2026) Health Canada cleared Phase 2 study initiation for DM199 in preeclampsia
  • (May 2026) Four separate preeclampsia data readouts plus one FGR readout expected through end of 2027
  • (Q1 2026) $51.3M cash position provides runway through 2027; accumulated deficit $182.8M

Named Competitors

  • Acute Ischemic Stroke Therapeutics — Competing stroke therapy programs in Phase 2/3 development
  • Preeclampsia & FGR Treatments — Maternal vascular disease therapeutic candidates

Recent Developments

  • (May 2026) ReMEDy2 Phase 2/3 AIS trial surpassed 70% of required interim enrollment
  • (March 2026) Received Health Canada regulatory approval for Phase 2 DM199 preeclampsia study
  • (Q1 2026) DM199 Preeclampsia Phase 2 IST Part 1a expansion cohort enrolling; updated dataset expected Q2 2026
  • (Full Year 2025) Initiated investigator-sponsored trial expansion cohorts for preeclampsia program

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