Schrödinger, Inc. — Cyborg Score 7/10

Strong
Computational Science / Biotech Software

Strategic Profile

The platform is designed to accelerate R&D by predicting molecular properties, reducing the time and cost required to bring new products to market. Once integrated into large pharma's R&D workflow, the platform becomes a mission-critical tool with high switching costs.

Cyborg Score Rationale

2025 total revenue reached $255.9M (up 23.3%) with software revenue of $199.5M and software ACV of $198.5M. Strong growth trajectory and high-margin software business offset profitability challenges, with management targeting positive adjusted EBITDA by 2028.

Top Insights

  • Key 2025 milestones include strategic agreements with Lilly and Manas AI, a beta Predictive Toxicology solution, 20 peer-reviewed publications, and initial Phase 1 clinical data for SGR-1505.
  • Company is accelerating transition to licensing model with full-year 2025 revenue up 23.3% to $255.9M, driven by 10.6% software revenue increase; drug discovery revenue more than doubled to $56.4M.
  • 2026 guidance projects software revenue $218-228M (10-15% growth) and drug discovery revenue $55-65M.
  • Company combines physics-based simulations with AI and machine learning to address data scarcity challenges in drug discovery.

Named Competitors

  • Certara — Computational pharmacology and drug development software platform
  • Veeva Systems — Cloud software for life sciences R&D and commercial operations
  • Tempus AI — AI platform for oncology and precision medicine research

Recent Developments

  • (Feb 2026) Company granted inducement equity awards to newly hired employees including 9,600 stock options and 18,250 RSUs.
  • (Feb 2026) Reported 2025 progress including strategic agreements with Lilly and Manas AI plus Phase 1 clinical data for SGR-1505.
  • (Feb 2026) Delivered Q4 2025 results with robust revenue growth and announced acceleration of transition to licensing model for more predictable revenue.

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