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Gritstone bio, Inc.: Business Overview, Financials & Competitive Analysis

Gritstone bio, Inc. scores 2/10 on the AskCyborg Cyborg Score (Challenged). Early-stage immunotherapy platform with promising science undermined by critical financial failure and delisted status. The company filed for Chapter 11 bankruptcy in October 2024. Market capitalization stands at $3.8M with the stock declining 98.3% over the past year. The platform and pipeline remain scientifically interesting but company viability is.

What is Gritstone bio, Inc.'s industry? Gritstone bio, Inc. (gritstonebio.com) operates in Biotechnology - Immunotherapy & Oncology. AskCyborg classifies Gritstone bio, Inc. under Biotechnology - Immunotherapy & Oncology in its company registry.

Gritstone bio discovers, develops, manufactures and delivers next generation cancer and infectious disease immunotherapy candidates. The company uses self-amplifying mRNA (samRNA) and chimpanzee adenovirus (ChAd) vect...

2/ 10Challenged

Cyborg Score thesis

Early-stage immunotherapy platform with promising science undermined by critical financial failure and delisted...

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Industry Biotechnology - Immunotherapy & Oncology
3 named competitors
3 recent developments
11 analyst dimensions
Synthesized from analyst-debate stress-testing across 11 dimensions and hundreds of data points. Methodology →
Cyborg Score recalibrated: September 14, 2026
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Gritstone bio, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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Gritstone bio, Inc. Overview

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Gritstone bio discovers, develops, manufactures and delivers next generation cancer and infectious disease immunotherapy candidates. The company uses self-amplifying mRNA (samRNA) and chimpanzee adenovirus (ChAd) vectors to elicit desired immune responses. The company faces severe financial distress following bankruptcy restructuring.

Strategic Profile

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The company's two oncology programs in clinical-stage development are GRANITE, an individualized neoantigen-based immunotherapy, and SLATE, an off-the-shelf shared neoantigen-based immunotherapy. The company has also developed a COVID-19 vaccine candidate supported by U.S. government contracts and is researching a functional cure for HIV in collaboration with the National Institutes of Health.

Competitive Landscape

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Gritstone competes in the personalized cancer immunotherapy and vaccine development space against larger, better-capitalized biotechs including Moderna, BioNTech, and Inovio. However, bankruptcy and delisting have effectively removed it from active competition. The company's neoantigen-personalized approach competes conceptually with similar therapies from larger oncology platforms.

Industry Context

Gritstone bio, Inc. operates in Biotechnology - Immunotherapy & Oncology.

Key facts

Founded: 2015 · Headquarters: Emeryville, US · Market cap: $3.8M

What the analysts stress-tested

The top findings that survived the multi-agent debate for Gritstone bio, Inc..

  • Proprietary samRNA and ChAd vector platforms target cancer neoantigens and infectious diseases
  • Significant financial deterioration: Chapter 11 bankruptcy filed (October 2024), stock down 98.3% year-over-year
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Recent developments

Material events tracked by the AskCyborg corpus.

  • October 2024Filed for Chapter 11 bankruptcy
  • Stock price declined to penny stock levels (below $0.05 by late 2024)
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Named competitors

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Industry context

Gritstone bio, Inc. operates in Biotechnology - Immunotherapy & Oncology. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does Gritstone bio, Inc. do?+
Gritstone bio discovers, develops, manufactures and delivers next generation cancer and infectious disease immunotherapy candidates. The company uses self-amplifying mRNA (samRNA) and chimpanzee adenovirus (ChAd) vect...
What is Gritstone bio, Inc.'s Cyborg Score?+
Gritstone bio, Inc. has a Cyborg Score of 2/10 (Challenged). The score synthesizes business model, financials, leadership, competitive position, technology, marketing, and ESG dimensions across hundreds of data points.
Who are Gritstone bio, Inc.'s main competitors?+
Named competitors include Moderna, BioNTech, Inovio. The full competitive landscape is in the AskCyborg report.
How can I get the full Gritstone bio, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the Gritstone bio, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.

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