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Astria Therapeutics, Inc.: Business Overview, Financials & Competitive Analysis

Astria Therapeutics is a biopharmaceutical company engaged to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Its lead program, STAR-0215 (navenib...

Cyborg Score recalibrated: September 28, 2026
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Astria Therapeutics, Inc. OverviewStrategic ProfileCompetitive LandscapeIndustry ContextKey facts
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Astria Therapeutics, Inc. Overview

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Astria Therapeutics is a biopharmaceutical company engaged to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Its lead program, STAR-0215 (navenibart), is a monoclonal antibody inhibitor of plasma kallikrein in late-stage development for hereditary angioedema (HAE).

Strategic Profile

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The acquisition strengthens BioCryst's position as a leader in hereditary angioedema and enhances long-term growth trajectory. Navenibart is a late-stage, long-acting plasma kallikrein inhibitor currently in Phase 3 clinical development with potential to be the first HAE therapy with every-three and every-six month dosing.

Competitive Landscape

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Astria competed in the rare disease biopharmaceutical space, specifically in hereditary angioedema therapies. Prior to acquisition, navenibart competed against existing HAE treatments including established plasma kallikrein inhibitors and other HAE therapies. BioCryst's acquisition reflects the strategic value of this late-stage asset in a growing HAE treatment market.

Industry Context

Astria Therapeutics, Inc. operates in Pharmaceuticals.

Key facts

Founded: 2008 · Headquarters: Boston, MA · Revenue: Pre-commercial (no product revenue; development-stage company)

What the analysts stress-tested

The top findings that survived the multi-agent debate for Astria Therapeutics, Inc..

  • (January 2026) Acquisition completed by BioCryst valued Astria at approximately $920M equity and $700M enterprise value, adding a Phase 3 HAE candidate with differentiated dosing profile to BioCryst's rare disease portfolio.
  • (November 2025) Positive ALPHA-STAR Phase 1b/2 trial results with 29 HAE patients demonstrated clinical viability of navenibart before acquisition closure, supporting regulatory pathway forward.
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Recent developments

Material events tracked by the AskCyborg corpus.

  • January 2026BioCryst acquisition completed
  • January 2026Astria stockholders voted to approve acquisition
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Named competitors

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Industry context

Astria Therapeutics, Inc. operates in Pharmaceuticals. See how the rest of the sector scores on the Cyborg framework.

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Frequently asked questions

What does Astria Therapeutics, Inc. do?+
Astria Therapeutics is a biopharmaceutical company engaged to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Its lead program, STAR-0215 (navenib...
What is Astria Therapeutics, Inc.'s Cyborg Score?+
The Cyborg Score is a 1-10 rating from the AskCyborg multi-agent analyst-debate framework. Recalibrated weekly across business, financials, leadership, competitive position, technology, marketing, and ESG dimensions.
Who are Astria Therapeutics, Inc.'s main competitors?+
Named competitors include BioCryst Pharmaceuticals. The full competitive landscape is in the AskCyborg report.
How can I get the full Astria Therapeutics, Inc. research report?+
Get the report plus analyst-debate audio at askcyborg.com -- no credit card required for preview access. Pro adds saved-company audio playlists and monitoring.
How current is the Astria Therapeutics, Inc. research?+
The Cyborg Score is recalibrated weekly. Recent developments are tracked continuously and surfaced in every report.