VivoSim Labs, Inc. (formerly Organovo Holdings, Inc.) — Cyborg Score 3/10

Challenged
Drug Discovery Services

Strategic Profile

The company's 3D human tissue platform includes proprietary NovoGen Bioprinters, which are automated devices that enable the fabrication of 3D living tissues comprised of mammalian cells, and related technologies for preparing bio-inks and bioprinting multicellular tissues with complex architecture. The company changed its name from Organovo Holdings, Inc. to VivoSim Labs, Inc. in April 2025, reflecting a strategic focus on its core bioprinting mission.

Cyborg Score Rationale

The company is quickly burning through cash, with a concerning current ratio of 0.72 and weak overall financial health score. As of September 30, 2025, VivoSim Labs has a trailing 12-month revenue of $140K, indicating severe revenue challenges for a clinical-stage biotech.

Top Insights

  • Lead candidate FXR314 is in phase 2/3 clinical trial for inflammatory bowel disease with clinical focus on ulcerative colitis and completed phase 1 clinical trial for liver fibrosis with focus on steatohepatitis
  • In January 2026, VivoSim expanded Asia-Pacific access to NAMKind human-based toxicology services through a new distributor agreement in Korea and China
  • Market cap is $7.02M as of October 31, 2025 with 2.61M shares outstanding, indicating severe market skepticism
  • Company has 13 total employees, suggesting minimal operational scale

Named Competitors

  • 3D Tissue Engineering — Alternative 3D tissue models for drug discovery
  • Organ-on-a-Chip Platform — Microfluidic human tissue models
  • iPSC-derived Tissues — Induced pluripotent stem cell-based therapeutics

Recent Developments

  • (January 2026) VivoSim expanded Asia-Pacific distribution for toxicology services in Korea and China
  • (April 2025) Completed rebranding from Organovo Holdings to VivoSim Labs with ticker change from ONVO to VIVS

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